منابع مشابه
Rapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series
Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
متن کاملRapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series
Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
متن کاملSkin models for the testing of transdermal drugs
The assessment of percutaneous permeation of molecules is a key step in the evaluation of dermal or transdermal delivery systems. If the drugs are intended for delivery to humans, the most appropriate setting in which to do the assessment is the in vivo human. However, this may not be possible for ethical, practical, or economic reasons, particularly in the early phases of development. It is th...
متن کاملSalbutamol-Induced Desensitization and Attempts to Resensitize In Vitro
The study was carried out to desensitize spontaneously active isolated chick rectum with salbutamol in log doses starting from 100 nanogram and resensitize with various drugs as a result to revive the desensitized tissue and respond to Salbutamol. The tissue response after desensitization to alpha, beta adrenergic and muscarinic acetylcholine receptor antagonists was isotonically recorded for 1...
متن کاملSurvey of Drug Allergy Testing, Challenge, and Desensitization Practice
Background: The lack of standardized skin test products to determine a patient’s (hyper-) sensitivity to medications has required physicians to empirically develop their own testing procedures. These approaches include puncture and intradermal skin tests, patch tests and medication challenges. Desensitization protocols are also frequently used when the necessity of a particular medication is ur...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1962
ISSN: 0035-9157
DOI: 10.1177/003591576205500113